Tzu Chi Medical hosts a dental outreach in Las Vegas, Nevada in December 2021, using updated workflows and equipment to provide improved service for uninsured and underinsured patients.

As of October 29, 2021, the U.S. Food and Drug Administration approved the use of Pfizer-BioNTech COVID-19 vaccines for children aged 5 through 11, offering millions of children and families a way to help protect themselves against the spread of COVID-19 — while also supporting communities, and paving the way toward regaining a greater sense of normalcy. With this, Tzu Chi Medical Foundation (TCMF) immediately began contacting school districts in Southern California. Soon, Mountain View School District in El Monte, CA, joined Valle Lindo School District in South El Monte, CA, in administering the vaccine to parents and students at the Valle Lindo School District Office and Madrid Middle School. The community vaccination event took place on November 19 and November 20, and a total of 334 doses were given.

Despite going through years of economic struggle, California resident Jiang Yu relies on medical and emotional support from the Buddhist Tzu Chi Medical Foundation.